Heat oven to 350℉ (175℃).
Spray a 9 inch loaf pan with baking spray. Set aside.
Whisk together flour, baking powder, baking soda, salt, and lemon zest. Set aside.
Beat butter and sugar with an electric mixer until fluffy, about 2-3 minutes.
Add eggs, one at a time, beating well after each addition.
Add flour mixture alternately with milk, beginning and ending with flour mixture.
Mix in lemon juice, vanilla, and poppy seeds.
Pour into prepared loaf pan.
Bake for 45-50 minutes, or until loaf tests done, covering after 30 minutes, if needed, to prevent over browning,
Let cool in pan for 10-15 minutes.
Turn out on cooling rack.